Cyclohexanecarbonyl chloride → Benzimidazole

HRID 1072535Notizen

Reaktionsgleichung

NC1C=CC([C:8]2[NH:9][C:10]3[CH:16]=[CH:15][C:14](N)=[CH:13][C:11]=3[N:12]=2)=CC=1.C1(C(Cl)=O)CCCCC1>>[N:9]1[C:10]2[CH:16]=[CH:15][CH:14]=[CH:13][C:11]=2[NH:12][CH:8]=1

Komponenten

Edukt 2

HCID 75938Cyclohexanecarbonyl chloride

HCID 178507432HCID 178507432, Verbindung

Produkt 1

HCID 5798Benzimidazole

Versuchsvorschrift

2-(N-Cyclohexylcarbonyl-4′-aminophenyl)-6-cyclohexylcarbonylamino)-benzimidazole was prepared by Method A from 2-(4-aminophenyl)-6-aminobenzimidazole (0.195 g, 0.87 mmole) and cyclohexylcarbonyl chloride (0.291 ml, 0.319 g, 2.175 mmole). The resulting solid (76.7 mg) was purified by preparative HPLC.

Aufarbeitung

customThe resulting solid (76.7 mg) was purified by preparative HPLC

Quellen und Nachweise

ORD-Eintrag: ord-846edf29646848ffb9b26b83d99d7e9d
Quelldatensatz: uspto-grants-2005_06
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US06911462B2

Notizen zur Reaktion

Wird geladen…