2-(4-Benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole → 4-[5-Methyl-1-(4-pentylphenylpropyl)-1H-pyrrol-2-yl]phenol

HRID 1072718Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1072718
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([C:15]2[N:16]([CH2:21][CH2:22][CH2:23][C:24]3[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=3)[C:17]([CH3:20])=[CH:18][CH:19]=2)=[CH:11][CH:10]=1)C1C=CC=CC=1>C(O)C.[C].[Pd]>[CH3:20][C:17]1[N:16]([CH2:21][CH2:22][CH2:23][C:24]2[CH:29]=[CH:28][C:27]([CH2:30][CH2:31][CH2:32][CH2:33][CH3:34])=[CH:26][CH:25]=2)[C:15]([C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)=[CH:19][CH:18]=1

Komponenten

4

Edukt 1

HCID 697319892-(4-Benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole

Produkt 1

HCID 697326774-[5-Methyl-1-(4-pentylphenylpropyl)-1H-pyrrol-2-yl]phenolAusbeute 54 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

To a solution of 2-(4-benzyloxyphenyl)-5-methyl-1-(4-pentylphenylpropyl)-1H-pyrrole (2.99 g, 6.6 mmol) in ethanol (60 ml) was added 10% palladium carbon (300 mg) and the mixture was stirred under hydrogen atmosphere. The insoluble matter was filtered out and the filtrate was concentrated to give the object compound as an oily substance. 1.28 g, (yield 54% )

Aufarbeitung

  1. filtrationThe insoluble matter was filtered out
  2. concentrationthe filtrate was concentrated
  3. customto give the object compound as an oily substance

Quellen und Nachweise

ORD-Eintrag
ord-18ae5b44f76f4f6fa55d1553d4ba9813
Quelldatensatz
uspto-grants-2005_06
Patentnummer
US06911468B2

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