HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methylamine → HCID 178482511, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methylamine | HCID 6329 | — |
| Edukt | (3-Mercaptopropyl)ammonium chloride | HCID 197870 | — |
| Edukt | (2-((Dimethylamino)methyl)thiazol-4-yl)methanol | HCID 1838020 | — |
| Edukt | 3,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide | HCID 12230538 | — |
| Lösungsmittel | Hydrogen Bromide | HCID 260 | — |
| Produkt | HCID 178482511 | HCID 178482511 | — |
Reaktionsschritte
When 2-dimethylaminomethyl-4-hydroxymethylthiazole [prepared in Example 34, Step D] is reacted with 3-mercaptopropylamine hyrochloride [prepared according to the procedure described in J. Org. Chem., 27, 2846 (1962)] in aqueous hydrobromic acid (48%), and the resultant amine is successively treated with 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide and excess methylamine as in the general procedure of Example 31, the title compound is produced.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04394508 |
| Quelldatensatz | uspto-grants-1983_07 |
| ORD ID | ord-18c292dfca954221bfdf601dfca5224e |
| Quellennotiz | uspto-grants-1983_07 |