Hydrochloric Acid → HCID 178526043, Verbindung
Reaktionsgleichung
C([O:3][C:4]([CH2:6][S:7][C:8]1[C:13]([F:14])=[CH:12][NH:11][C:10](=[O:15])[N:9]=1)=[O:5])C.Cl>[OH-].[K+]>[C:4]([CH2:6][S:7][C:8]1[C:13]([F:14])=[CH:12][NH:11][C:10](=[O:15])[N:9]=1)([OH:5])=[O:3]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
4-Ethoxycarbonylmethylthio-5-fluoropyrimid-2-one (0.0013 mol) in 2 M potassium hydroxide (4 ml) was heated on a waterbath for 5-6 min. The solution was allowed to cool before neutralisation with dilute hydrochloric acid. The precipitated solid was recrystallised from methanol: yield 41%, m.p. 255° C.
Aufarbeitung
- customThe precipitated solid was recrystallised from methanol
Quellen und Nachweise
- ORD-Eintrag
- ord-d9ba412572a149cb87ceef334b74ce45
- Quelldatensatz
- uspto-grants-1983_07
- Patentnummer
- US04395406
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