1-(4-Chlorobutyl)-1-methyl-5-methoxy-2tetralone → 6,7,8,9,10,11-Hexahydro-1-Methoxy-5-Methyl-5,10-Methano-5H-Benzocyclononen-12-One
Reaktionsgleichung
COC1C=CC2CC3C(=O)C(C)(C=2C=1)CCCC3.Cl[CH2:20][CH2:21][CH2:22][CH2:23][C:24]1([CH3:37])[C:33]2[C:28](=[C:29]([O:34][CH3:35])[CH:30]=[CH:31][CH:32]=2)[CH2:27][CH2:26][C:25]1=[O:36]>>[CH3:35][O:34][C:29]1[C:28]2[CH2:27][CH:26]3[C:25](=[O:36])[C:24]([CH3:37])([C:33]=2[CH:32]=[CH:31][CH:30]=1)[CH2:23][CH2:22][CH2:21][CH2:20]3Komponenten
3
Versuchsvorschrift
Using a procedure analogous to that described in Example X for the preparation of 6,7,8,9,10,11-hexahydro-3-methoxy-5-methyl- 5,10-methano-5H-benzocyclononen-12-one, there is obtained from 40.5 g. of 1-(4-chlorobutyl)-1-methyl-5-methoxy-2-tetralone, 21.5 g. of the title product, b.p. 130° to 135° C. (0.3 mm.).
Aufarbeitung
- customthere is obtained from 40.5 g