13beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one → Einecs 227-699-7

HRID 1077154

Reaktionsgleichung

Reaktionsgleichung von HRID 1077154
[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C:7]1=[CH:6][CH2:5][C:4]2=[O:22])[CH3:2].[H][H]>O1CCOCC1.[Ni]>[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([O:20][CH3:21])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C@@H:7]1[CH2:6][CH2:5][C:4]2=[O:22])[CH3:2]

Komponenten

5

Edukt 2

HCID 1097930013beta-Ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-oneHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 111113Einecs 227-699-7Ausbeute 59,6 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 312751,4-DioxaneLösungsmittel

Versuchsvorschrift

Dissolve 13β-ethyl-3-methoxygona-1,3,5(10),8,14-pentaen-17-one (2 g) in dioxan (50 cc) containing Raney nickel (ca. 0.5 g) of moderate activity and shake with hydrogen until 160 cc., the amount corresponding to one molecular proportion has been absorbed. Recrystallize the isolated product from methanol to obtain the title product (1.2 g), m.p. 110°-125°; ultraviolet absorption peak at 280 mμ (ε13,200).

Aufarbeitung

  1. custom, the amount corresponding to one molecular proportion has been absorbed
  2. customRecrystallize the isolated product from methanol

Quellen und Nachweise

ORD-Eintrag
ord-ff9bc7ab3fa4433da1e738ad694f2d4a
Quelldatensatz
uspto-grants-1976_05
Patentnummer
US03959322

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