5,6-Diamino-1,3-dimethyluracil → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,3-dimethoxyphenyl)ethenyl)-1,3-dimethyl-, (E)-

HRID 1077490

Reaktionsgleichung

Reaktionsgleichung von HRID 1077490
[NH2:1][C:2]1[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=1[NH2:8].[CH3:13][O:14][C:15]1[C:25]([O:26][CH3:27])=[CH:24][CH:23]=[CH:22][C:16]=1[CH:17]=[CH:18][C:19](O)=O>>[CH3:13][O:14][C:15]1[C:25]([O:26][CH3:27])=[CH:24][CH:23]=[CH:22][C:16]=1/[CH:17]=[CH:18]/[C:19]1[NH:1][C:2]2[C:3](=[O:12])[N:4]([CH3:11])[C:5](=[O:10])[N:6]([CH3:9])[C:7]=2[N:8]=1

Komponenten

3

Edukt 2

HCID 795015,6-Diamino-1,3-dimethyluracilHCID 995252,3-Dimethoxycinnamic acid

Produkt 1

HCID 53792321H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,3-dimethoxyphenyl)ethenyl)-1,3-dimethyl-, (E)-

Versuchsvorschrift

Substantially the same procedure as in Reference Example 70 was repeated using 2.50 g (14.7 mmol) of 5,6-diamino-1,3-dimethyluracil and 3.37 g (16.2 mmol) of 2,3-dimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from ethanol/water to give 1.03 g (yield of Compound 97 as pale yellow needles.

Aufarbeitung

  1. customThen, the resultant crude crystals were recrystallized from ethanol/water

Quellen und Nachweise

ORD-Eintrag
ord-e326f5bdacc54f0ab5ee50ec6e3e2afd
Quelldatensatz
uspto-grants-1996_08
Patentnummer
US05543415

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