HCID 3126210, Verbindung → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-butoxyphenyl)ethenyl)-1,3-diethyl-, (E)-

HRID 1077514Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1077514
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[CH2:15]([O:19][C:20]1[CH:30]=[CH:29][C:23]([CH:24]=[CH:25][C:26](O)=O)=[CH:22][CH:21]=1)[CH2:16][CH2:17][CH3:18]>>[CH2:15]([O:19][C:20]1[CH:21]=[CH:22][C:23](/[CH:24]=[CH:25]/[C:26]2[NH:1][C:2]3[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=3[N:8]=2)=[CH:29][CH:30]=1)[CH2:16][CH2:17][CH3:18]

Komponenten

3

Edukt 2

HCID 3126210HCID 3126210, VerbindungHCID 45721335,6-Diamino-1,3-diethyluracil

Produkt 1

HCID 64488801H-Purine-2,6-dione, 3,7-dihydro-8-(2-(4-butoxyphenyl)ethenyl)-1,3-diethyl-, (E)-

Versuchsvorschrift

Substantially the same procedure as in Reference Example 70 was repeated using 3.00 g (15.1 mmol) of 5,6-diamino-1,3-diethyluracil and 3.67 g (16.7 mmol) of 4-butoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 3.04 g (yield of Compound 147 as pale yellow needles.

Aufarbeitung

  1. customThen, the resultant crude crystals were recrystallized from dioxane/water

Quellen und Nachweise

ORD-Eintrag
ord-e6fbaa0603db46d6bd3ecadb20a0199c
Quelldatensatz
uspto-grants-1996_08
Patentnummer
US05543415

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