1,2-Dichloro-4-nitrobenzene → 2-Chloro-1-fluoro-4-nitrobenzene

HRID 1078054

Reaktionsgleichung

Reaktionsgleichung von HRID 1078054
[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1Cl.[F-:12].[K+]>[Cl-].C([N+](CCCCCCCCCCCCCCCCCC)(C)C)CCCCCCCCCCCCCCCCC>[Cl:1][C:2]1[CH:3]=[C:4]([N+:9]([O-:11])=[O:10])[CH:5]=[CH:6][C:7]=1[F:12]

Komponenten

4

Edukt 2

HCID 74431,2-Dichloro-4-nitrobenzeneHCID 522689Potassium Fluoride

Produkt 1

HCID 676882-Chloro-1-fluoro-4-nitrobenzeneAusbeute 69 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7879Distearyldimethylammonium chlorideKatalysator

Versuchsvorschrift

576 g (3 mol) of 3,4-dichloronitrobenzene, 58 g (0.1 mol) of distearyldimethylammonium chloride and 139 g (2.4 mol) of potassium fluoride were reacted analogously to Example 1. After filtering with suction, the residue was dissolved in water, the organic phase was separated off and the combined organic phases were fractionated. 289 g (69%, relative to potassium fluoride employed) of 3-chloro-4-fluoronitrobenzene were obtained.

Aufarbeitung

  1. filtrationAfter filtering with suction
  2. dissolutionthe residue was dissolved in water
  3. customthe organic phase was separated off

Quellen und Nachweise

ORD-Eintrag
ord-e30add03b270414caea64b94a829809e
Quelldatensatz
uspto-grants-1996_08
Patentnummer
US05545768

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