Piperazine → HCID 19429145, Verbindung
Reaktionsgleichung
[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9](Cl)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1.[NH:19]1[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]1>>[CH3:1][C:2]([CH3:18])([CH3:17])[CH2:3][NH:4][C:5]1[N:10]=[C:9]([N:19]2[CH2:24][CH2:23][NH:22][CH2:21][CH2:20]2)[CH:8]=[C:7]([N:12]2[CH2:16][CH2:15][CH2:14][CH2:13]2)[N:6]=1Komponenten
3
Versuchsvorschrift
(2,2-Dimethylpropylamino)-4-chloro-6-pyrrolidinopyrimidine is reacted with piperazine as described in Example 5 to obtain the title compound in a yield of 76%, m.p.:118°-120° C.
Quellen und Nachweise
- ORD-Eintrag
- ord-a2317be09eba43d8b0d2dd93b1dab6a8
- Quelldatensatz
- uspto-grants-1996_08
- Patentnummer
- US05547949
Notizen zur Reaktion
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