m-Anisoyl chloride → 3-Methoxybenzamide

HRID 1078362

Reaktionsgleichung

Reaktionsgleichung von HRID 1078362
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6](Cl)=[O:7].C([O-])(=O)C.[NH4+:16]>CC(C)=O.ClCCl>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([NH2:16])=[O:7]

Komponenten

5

Edukt 2

HCID 74374m-Anisoyl chlorideHCID 517165Ammonium Acetate

Produkt 1

HCID 984873-MethoxybenzamideAusbeute 49,8 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 180AcetoneLösungsmittelHCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

17 g of 3-methoxybenzoyl chloride were dissolved in 200 ml acetone. 15.5 g of ammonium acetate were added to the solution and the reaction mixture was stirred for several hours at room temperature. Then it was dissolved in dichloromethane. The dichloromethane phase was dried by adding sodium carbonate and concentrated. 7.5 g of 3-methoxybenzamide were obtained as a colorless solid.

Aufarbeitung

  1. dry with materialThe dichloromethane phase was dried
  2. additionby adding sodium carbonate
  3. concentrationconcentrated

Quellen und Nachweise

ORD-Eintrag
ord-228169d585f3459db6433751facf9e90
Quelldatensatz
uspto-grants-1996_08
Patentnummer
US05547967

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