Nitric Acid → 2-Nitroimino-3-(4-pyridylmethyl)thiazolidine

HRID 1079429Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1079429
[NH:1]=[C:2]1[N:6]([CH2:7][C:8]2[CH:13]=[CH:12][N:11]=[CH:10][CH:9]=2)[CH2:5][CH2:4][S:3]1.[N+:14]([O-])([OH:16])=[O:15]>S(=O)(=O)(O)O>[N+:14]([N:1]=[C:2]1[N:6]([CH2:7][C:8]2[CH:9]=[CH:10][N:11]=[CH:12][CH:13]=2)[CH2:5][CH2:4][S:3]1)([O-:16])=[O:15]

Komponenten

4

Edukt 2

HCID 944Nitric AcidHCID 139209202-Imino-3-(4-pyridylmethyl)thiazolidine

Produkt 1

HCID 543576062-Nitroimino-3-(4-pyridylmethyl)thiazolidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1118Sulfuric AcidLösungsmittel

Versuchsvorschrift

5.8 g of 2-imino-3-(4-pyridylmethyl)thiazolidine was added to 20 ml of conc. sulfuric acid at -5°~0° C. 6 ml of fuming nitric acid was then added dropwise to the solution at the same temperature. After stirring for 30 minutes at 0°~5° C., the reaction mixture was poured onto crushed ice. Twice extract with dichloromethane followed by treating in the usual way yielded 1.4 g of desired 2-nitroimino-3-(4-pyridylmethyl)thiazolidine.

Aufarbeitung

  1. additionthe reaction mixture was poured
  2. customonto crushed ice
  3. extractionTwice extract with dichloromethane
  4. additionby treating in the usual way

Quellen und Nachweise

ORD-Eintrag
ord-5ea00db880fd4e90bffcd1d8f821ac5b
Quelldatensatz
uspto-grants-1996_12
Patentnummer
US05580889

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