2-Propenoic acid, 3-(methoxyphenyl)- → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2-methoxyphenyl)ethenyl)-, (E)-

HRID 1081785

Reaktionsgleichung

Reaktionsgleichung von HRID 1081785
[NH2:1][C:2]1[C:3](=[O:14])[N:4]([CH2:12][CH3:13])[C:5](=[O:11])[N:6]([CH2:9][CH3:10])[C:7]=1[NH2:8].[CH3:15][O:16][C:17]1[CH:27]=[CH:26][CH:25]=[CH:24][C:18]=1[CH:19]=[CH:20][C:21](O)=O>>[CH2:12]([N:4]1[C:3](=[O:14])[C:2]2[NH:1][C:21](/[CH:20]=[CH:19]/[C:18]3[CH:24]=[CH:25][CH:26]=[CH:27][C:17]=3[O:16][CH3:15])=[N:8][C:7]=2[N:6]([CH2:9][CH3:10])[C:5]1=[O:11])[CH3:13]

Komponenten

3

Edukt 2

HCID 268622-Propenoic acid, 3-(methoxyphenyl)-HCID 45721335,6-Diamino-1,3-diethyluracil

Produkt 1

HCID 64488841H-Purine-2,6-dione, 3,7-dihydro-1,3-diethyl-8-(2-(2-methoxyphenyl)ethenyl)-, (E)-Ausbeute 24 %

Versuchsvorschrift

Substantially the same procedure as in Example 7 was repeated using 2.5 g (12.6 mmol) of 5,6-diamino-1,3-diethyluracil and 2.48 g (13.9 mmol) of 2-methoxycinnamic acid. Then, the resultant crude crystals were recrystallized from tetrahydrofuran/water to give 990 mg (yield 24%) of Compound 108 as yellow grains.

Aufarbeitung

  1. customThen, the resultant crude crystals were recrystallized from tetrahydrofuran/water

Quellen und Nachweise

ORD-Eintrag
ord-b4d7851434364fa1854e5b0a5c99c00a
Quelldatensatz
uspto-grants-1996_12
Patentnummer
US05587378

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