3-(3-Chlorophenyl)prop-2-enoic acid → (E)-8-(3-Chlorostyryl)-1,3-diethylxanthine

Beteiligte Stoffe

Reaktionsschritte

Substantially the same procedure as in Example 7 was repeated using 3.50 g (17.7 mmol) of 5,6-diamino-1,3-diethyluracil and 3.55 g (19.4 mmol) of 3-chlorocinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 2.57 g (yield 42%) of Compound 132 as white plates.

Herkunft & Nachweise