HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Cyanamide → {4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-fluoro-phenyl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Cyanamide | HCID 9864 | — |
| Edukt | 3-Fluorophenacyl bromide | HCID 2737451 | — |
| Edukt | 1-(4-Isothiocyanatophenyl)-4-cyclopropylmethylpiperazine | HCID 21958916 | — |
| Produkt | {4-Amino-2-[4-(4-cyclopropylmethyl-piperazin-1-yl)-phenylamino]-thiazol-5-yl}-(3-fluoro-phenyl)-methanone | HCID 10297718 | — |
Reaktionsschritte
This compound was prepared from cyanamide, 1-(4-isothiocyanatphenyl)-4-cyclopropylmethylpiperazine (of Example 14G) and 2-bromo-1-(3-fluorophenyl)ethanone (Aldrich) following the procedure used in Example 24 Mass spectrum (ES) MH+=452.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07094896B2 |
| Quelldatensatz | uspto-grants-2006_08 |
| ORD ID | ord-04d595ef5af24223bfc0b9fd7caf593a |
| Quellennotiz | uspto-grants-2006_08 |