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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1082575Erstellt: 24. Oktober 2026

Decyl chloroformate → Phthalimide hydrochloride

https://huagongshe.com/de/reaction/1082575

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktDecyl chloroformateHCID 108727—
EduktN-[2-[4-(6-fluoro1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimideHCID 18467209—
LösungsmittelDiethyl EtherHCID 3283—
ProduktPhthalimide hydrochlorideHCID 22266261—

Reaktionsschritte

A mixture of decanyl chloroformate (2.4 g, 11 mmol), and N-[2-[4-(6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide (3.9 g, 10 mmol) was warmed on the steam bath for 15 minutes. The reaction was allowed to cool to ambient temperature, and then ether was added to the residue. The resulting solid was filtered to afford N-2-[4-(1-decanoxy-6-fluoro-1H-indazol-3-yl)-1-piperazinyl]ethyl]phthalimide hydrochloride.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05589494
Quelldatensatzuspto-grants-1996_12
ORD IDord-2c72f61da3c04644908d462ed26b2a58
Quellennotizuspto-grants-1996_12