Hydrochloric Acid → HCID 13588718, Verbindung

HRID 1084955

Reaktionsgleichung

Reaktionsgleichung von HRID 1084955
Br[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][O:8][CH2:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.Cl.[CH2:18]([NH2:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[C:11]1([CH2:10][CH2:9][O:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:25][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Komponenten

4

Edukt 3

HCID 313Hydrochloric AcidHCID 7504BenzylamineHCID 13375574[2-[(6-Bromohexyl)oxy]ethyl]benzene

Produkt 1

HCID 13588718HCID 13588718, Verbindung

Versuchsvorschrift

[2-[(6-Bromohexyl)oxy]ethyl]benzene (4.0 g) was added dropwise to benzylamine (20 ml) at 110°. The solution was heated at 110°-120° for 90 min, cooled, and treated with hydrochloric acid (2M; 125 ml). The mixture was extracted with EA (2×100 ml) and the extract was washed with aqueous sodium carbonate (100 ml) and brine (100 ml), dried and evaporated. Distillation of the residue gave the title compound as a colourless oil (3.2 g) b.p. 180°-190°/0.1 mmHg. T.l.c. (CX-ER 1:1) Rf 0.25.

Aufarbeitung

  1. temperatureThe solution was heated at 110°-120° for 90 min
  2. temperaturecooled
  3. extractionThe mixture was extracted with EA (2×100 ml)
  4. washthe extract was washed with aqueous sodium carbonate (100 ml) and brine (100 ml)
  5. customdried
  6. customevaporated
  7. distillationDistillation of the residue

Quellen und Nachweise

ORD-Eintrag
ord-701e52f0837a4296b1c0c367b66917b6
Quelldatensatz
uspto-grants-1991_04
Patentnummer
US05006556

Verknüpfte Notizen

Wird geladen…