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HRID 10850Erstellt: 24. Oktober 2026

4-Chlorophthalic anhydride → Methyl 3-(5-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate

https://huagongshe.com/de/reaction/10850

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt4-Chlorophthalic anhydrideHCID 67044—
EduktMethyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982209—
ProduktMethyl 3-(5-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionateHCID 21982220—

Reaktionsschritte

Methyl 3-(5-chloro-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-(2-methyl-[1,3]dioxolan-2-yl)propionate was prepared (0.54 g, 73%) in the same manner as described in the above example 5 (1) from methyl 3-amino-2-(2-methyl-[1,3]dioxolan-2-yl)propionate (0.40 g, 2.11 mmol) and 4-chlorophthalic anhydride (0.50 g, 2.74 mmol), and the obtained product was identified with the following NMR data.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07094908B2
Quelldatensatzuspto-grants-2006_08
ORD IDord-ba36ac71896c4e299590b9da60b729a0
Quellennotizuspto-grants-2006_08