1,3-dimethyl-6-{2-[2-(4-nitrophenyl)ethylamino]-ethylamino}-2,4(1H,3H)-pyrimidinedione → 1,3-dimethyl-6-[2-(4-nitrobenzylamino)ethylamino]-2,4(1H,3H)-pyrimidinedione
Reaktionsgleichung
CN1C(NCCCNC2C=CC([N+:19]([O-:21])=[O:20])=CC=2)=CC(=O)N(C)C1=O.[CH3:25][N:26]1[C:31]([NH:32][CH2:33][CH2:34][NH:35][CH2:36][CH2:37][C:38]2[CH:43]=[CH:42][C:41]([N+]([O-])=O)=[CH:40]C=2)=[CH:30][C:29](=[O:47])[N:28]([CH3:48])[C:27]1=[O:49]>>[CH3:25][N:26]1[C:31]([NH:32][CH2:33][CH2:34][NH:35][CH2:36][C:37]2[CH:38]=[CH:43][C:42]([N+:19]([O-:21])=[O:20])=[CH:41][CH:40]=2)=[CH:30][C:29](=[O:47])[N:28]([CH3:48])[C:27]1=[O:49]Komponenten
3
Versuchsvorschrift
The same procedure as in Example 2 was repeated with the exception that 1,3-dimethyl-6-(piperazin-1-yl)-2,4-(1H,3H)-pyrimidinedione (compound 2) was replaced with 0.45 g of 6-(2-aminoethylamino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione (compound 13), in order to obtain 1,3-dimethyl-6-[2-(4-nitrobenzylamino)ethylamino]-2,4(1H,3H)-pyrimidinedione.