2-(2,4-Dichlorophenoxy)propanoyl chloride → 5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	2-(2,4-Dichlorophenoxy)propanoyl chloride	HCID 14303380	—
Edukt	5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine	HCID 18633458	—
Produkt	5'-[2(RS)-(2,4-dichlorophenoxy)propionamido]-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine	HCID 18633419	—

Reaktionsschritte

In an analogous manner, from 2(RS)-(2,4-dichlorophenoxy)propionyl chloride (prepared from the acid) and 5'-amino-2',5'-dideoxy-3'-O-ethyl-5-ethyluridine, there was obtained 5'-[2(RS)-(2,4 -dichlorophenoxy)propionamido]-2',5'-dideoxy-3'O-ethyl-5-ethyluridine of melting point 121°-124° C.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US05010060
Quelldatensatz	uspto-grants-1991_04
ORD ID	ord-a6532acda1d34b068ab10023e3045faa
Quellennotiz	uspto-grants-1991_04