Diethylamine → HCID 178455924, Verbindung

HRID 1086126Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1086126
C(NCC)C.[NH:6](C(OCC1C2C(=CC=CC=2)C2C1=CC=CC=2)=O)[C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:21])[NH2:20])=[O:12])[CH:8]([CH3:10])[CH3:9]>CN(C)C=O>[NH2:6][C@H:7]([C:11]([NH:13][C@H:14]([C:22]([NH:24][C@H:25]([C:30]([O:32][CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)=[O:31])[C@H:26]([CH2:28][CH3:29])[CH3:27])=[O:23])[CH2:15][CH2:16][CH2:17][NH:18][C:19](=[NH:20])[NH2:21])=[O:12])[CH:8]([CH3:10])[CH3:9]

Komponenten

4

Edukt 2

HCID 8021DiethylamineHCID 178455925HCID 178455925, Verbindung

Produkt 1

HCID 178455924HCID 178455924, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

31.5 ml of diethylamine are added to a solution of 21 g (30 mmol) of Fmoc-Val-Arg-Ile-OBzl in 200 ml of dimethylformamide. The mixture is left to stand at room temperature for 10 minutes, and is concentrated in vacuo. The residue is triturated with diethyl ether and filtered off with suction.

Aufarbeitung

  1. waitThe mixture is left
  2. concentrationis concentrated in vacuo
  3. customThe residue is triturated with diethyl ether
  4. filtrationfiltered off with suction

Quellen und Nachweise

ORD-Eintrag
ord-13a7e8668c1f49ed8ccba1ad01d60636
Quelldatensatz
uspto-grants-1991_04
Patentnummer
US05011825

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