3-Pyridineacrylic acid ethyl ester → 2-Propen-1-ol, 3-(3-pyridinyl)-

HRID 1088576

Reaktionsgleichung

Reaktionsgleichung von HRID 1088576
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][C:9](OCC)=[O:10])[CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=[CH:8][CH2:9][OH:10])[CH:2]=1

Komponenten

3

Edukt 2

HCID 5833373-Pyridineacrylic acid ethyl esterHCID 21226445Aluminium lithium hydride

Produkt 1

HCID 35635042-Propen-1-ol, 3-(3-pyridinyl)-

Versuchsvorschrift

Ethyl 3-(3-pyridyl)acrylate was reduced using lithium aluminum hydride to give 3-(3-pyridyl)-2-propen-1-ol. In 30 ml of acetone 710 mg of 3-(3-pyridyl)-2-propen-1-ol and 980 mg of methyl p-toluenesulfonate were heated under reflux for 22 hours. The reaction mixture was subjected by decantation to remove the solvent and then washed with acetone and ether. The residue was dried under reduced pressure to give 1.3 g of the desired compound as an orange-colored oil.

Quellen und Nachweise

ORD-Eintrag
ord-c33a204a8bac44d0aac96c9a5bb92baf
Quelldatensatz
uspto-grants-1990_10
Patentnummer
US04962096

Verknüpfte Notizen

Wird geladen…