Thionyl Chloride → 3-(1-Methylfluoren-9-yl)propionyl Chloride

HRID 1089854Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1089854
[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([OH:19])=O)[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1.O=S(Cl)[Cl:22]>>[CH3:1][C:2]1[C:14]2[CH:13]([CH2:15][CH2:16][C:17]([Cl:22])=[O:19])[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=3)[C:6]=2[CH:5]=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 150450953-(1-Methylfluoren-9-yl)propionic acid

Produkt 1

HCID 150450963-(1-Methylfluoren-9-yl)propionyl Chloride

Versuchsvorschrift

3-(1-Methylfluoren-9-yl)propionic acid (2.5 g, 9.9 mmol) was charged with SOCl2 (20 mL, in excess) at room temperature. The reaction mixture was boiled for 2 hr. Excess of thionyl chloride was removed under reduced pressure. The residual oil was used for the next step without further purification.

Aufarbeitung

  1. customExcess of thionyl chloride was removed under reduced pressure
  2. customThe residual oil was used for the next step without further purification

Quellen und Nachweise

ORD-Eintrag
ord-f72077c274bc48209040beb6f717b564
Quelldatensatz
uspto-grants-1992_01
Patentnummer
US05079260

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