Reaktionsgleichung
[SH:1][C:2]([CH3:12])([CH3:11])[CH2:3][NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1>[Tc]([O-])(=O)(=O)=O.[Na+]>[CH2:10]([S:1][C:2]([CH3:12])([CH3:11])[CH2:3][NH:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[NH:4][CH2:3][C:2]([SH:1])([CH3:12])[CH3:11])/[CH:5]=[CH:6]/[CH3:7]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
1-(2-trans-2-Butenylthio)-2-methylpropylamino)-2-(2-mercapto-2-methylpropylamino) benzene was reacted with Tc-99m sodium pertechnetate by the procedure of Example 7 to produce the Tc-99m complex of 1-[2-(trans-2-butenylthio)-2-methylpropylamino]-2-(2-mercapto-2-methylpropylamino) benzene. HPLC (90% ethanol//H2O, 1.5 ml/min, Waters Radial-Pak C-18) Rt 4.06 min, radiochemical purity 100%. TLC (70% hexane/diethyl ether) RF 0.26, radiochemical purity 94%. Electrophoresis (0.05 M NaH2PO4, pH 4.5, 300 volts, 45 min) neutral.
Quellen und Nachweise
- ORD-Eintrag
- ord-6be07f0df98d461889b18395d3dabcdb
- Quelldatensatz
- uspto-grants-1992_01
- Patentnummer
- US05080884
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