HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene → 2-Propanethiol, 1-anilino-2-methyl-
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene | HCID 10026859 | — |
| Katalysator | Sodium pertechnetate | HCID 74086836 | — |
| Produkt | 2-Propanethiol, 1-anilino-2-methyl- | HCID 143163 | — |
Reaktionsschritte
2-(2-(Butylthio)2-methylpropylamino]-1-(2-mercapto-2-methylpropylamino)benzene was reacted with Tc-99m sodium pertechnetate by the method of Example 7 to produce Tc-99m complex of 2-(2-butylthio)2-methylpropylamino)-1-(2-mercapto-2-methylpropylamino)benzene. The complex was purified by filtration through Millex GS and Jelco 5 micron fitlers. HPLC (90% ethanol/H 2 O, 1.5 ml/min, C18 5 micron Radial Pak) Rt 4.4 min (99%). TLC (50% diethyl ether/chloroform) Rf 0.89, radiochemical purity 92%. Electrophoresis (0.05 M NaH2PO4, buffer pH 4.5 constant 300 volts, 30 min) neutral.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05080884 |
| Quelldatensatz | uspto-grants-1992_01 |
| ORD ID | ord-18dad4edac2c4c8a9b8eae722bf37404 |
| Quellennotiz | uspto-grants-1992_01 |