1-(p-Chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochloride → 1-(p Chlorobenzyl)-5-fluoro-3-methylthioindole-2-propanoic acid
Reaktionsgleichung
Cl.[Cl:2][C:3]1[CH:18]=[CH:17][C:6]([CH2:7][N:8]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)N)=[CH:5][CH:4]=1.[CH3:19][S:20][CH2:21][C:22](=O)[CH2:23][CH2:24][C:25]([O:27]C)=[O:26]>C(O)(C)(C)C>[Cl:2][C:3]1[CH:18]=[CH:17][C:6]([CH2:7][N:8]2[C:10]3[C:15](=[CH:14][C:13]([F:16])=[CH:12][CH:11]=3)[C:21]([S:20][CH3:19])=[C:22]2[CH2:23][CH2:24][C:25]([OH:27])=[O:26])=[CH:5][CH:4]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
Following the procedure of Example 10, but using 1-(p-chlorobenzyl)-1-(4-fluorophenyl)hydrazine hydrochloride and methyl 5-methylthio-4-oxopentanoate as starting materials and t-butanol as the solvent, the title compound was prepared.