Ammonia → HCID 178491593, Verbindung

HRID 1091021Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1091021
[NH2:1][C:2]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11](=S)[NH:12][C:13](=[O:22])[C:14]1[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=1)=[O:3].N.OO>CO>[O:3]=[C:2]1[C:4]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[NH:10][C:11]([NH:12][C:13](=[O:22])[C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)=[N:1]1

Komponenten

5

Edukt 3

HCID 222AmmoniaHCID 784Hydrogen PeroxideHCID 8928142-[(4-Methoxybenzoyl)carbamothioylamino]benzamide

Produkt 1

HCID 178491593HCID 178491593, VerbindungAusbeute 10,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

To a stirred mixture of 9.9 g of the above benzamide, 100 ml of methanolic ammonia and 100 ml of methanol was added 22 ml of 30% hydrogen peroxide. The reaction was cooled because of an exotherm and then stirred overnight at room temperature. The solid was collected, partially dissolved in 800 ml of acetonitrile and filtered. The filtrate was chilled, giving 0.95 g of the desired product as white crystals, mp 235°-236° C. (dec.).

Aufarbeitung

  1. temperatureThe reaction was cooled because of an exotherm
  2. customThe solid was collected
  3. dissolutionpartially dissolved in 800 ml of acetonitrile
  4. filtrationfiltered
  5. temperatureThe filtrate was chilled

Quellen und Nachweise

ORD-Eintrag
ord-794b6dc04f7a436389072b3e9f0f8a8a
Quelldatensatz
uspto-grants-1992_01
Patentnummer
US05084457

Notizen zur Reaktion

Wird geladen…