Thiourea → 5-(3-Methanesulphonyl-phenyl)-4-methyl-thiazol-2-ylamine hydrobromide

HRID 1093016Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1093016
[Br:1][CH:2]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12]([CH3:15])(=[O:14])=[O:13])[CH:7]=1)[C:3](=O)[CH3:4].[NH2:16][C:17]([NH2:19])=[S:18]>>[BrH:1].[CH3:15][S:12]([C:8]1[CH:7]=[C:6]([C:2]2[S:18][C:17]([NH2:19])=[N:16][C:3]=2[CH3:4])[CH:11]=[CH:10][CH:9]=1)(=[O:14])=[O:13]

Komponenten

3

Edukt 2

HCID 2723790ThioureaHCID 858616531-Bromo-1-(3-methanesulphonyl-phenyl)-propanone

Produkt 1

HCID 865984455-(3-Methanesulphonyl-phenyl)-4-methyl-thiazol-2-ylamine hydrobromide

Versuchsvorschrift

A stirred solution of 1-bromo-1-(3-methanesulphonyl-phenyl)-propanone (176c) (0.32 g, 1.01 mmol) is treated with thiourea (0.067 g, 0.88 mmol) added in one portion. The reaction mixture is allowed to stir at room temperature over two days. The product precipitates out and is filtered to yield the tittle compound as while solid.

Aufarbeitung

  1. additionadded in one portion
  2. customThe product precipitates out
  3. filtrationis filtered
  4. customto yield the tittle compound as while solid

Quellen und Nachweise

ORD-Eintrag
ord-efcd0b8db4c141daa6ce6ce7087f38f3
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08129541B2

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