5-Propylthiophene-2-carboxylic acid → 2-Ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-phenol
Reaktionsgleichung
C([O:8][C:9]1[C:18]([CH3:19])=[CH:17][C:12]([C:13]([NH:15][NH2:16])=O)=[CH:11][C:10]=1[CH2:20][CH3:21])C1C=CC=CC=1.[CH2:22]([C:25]1[S:29][C:28]([C:30]([OH:32])=O)=[CH:27][CH:26]=1)[CH2:23][CH3:24]>>[CH2:20]([C:10]1[CH:11]=[C:12]([C:13]2[O:32][C:30]([C:28]3[S:29][C:25]([CH2:22][CH2:23][CH3:24])=[CH:26][CH:27]=3)=[N:16][N:15]=2)[CH:17]=[C:18]([CH3:19])[C:9]=1[OH:8])[CH3:21]Komponenten
3
Versuchsvorschrift
2-Ethyl-6-methyl-4-[5-(5-propyl-thiophen-2-yl)-[1,3,4]oxadiazol-2-yl]-phenol is prepared in analogy to Example 29 starting from 4-benzyloxy-3-ethyl-5-methyl-benzoic acid hydrazide and 5-propyl-thiophene-2-carboxylic acid; LC-MS: tR=0.99 min, [M+1]+=329.13.
Quellen und Nachweise
- ORD-Eintrag
- ord-090ca7c5f60e460fb0bd14d6f95763c3
- Quelldatensatz
- uspto-grants-2012_03
- DOI