Potassium Carbonate → 5-Chloro-2-[4-(2-hydroxy-ethoxy)-phenoxy]-benzaldehyde

Beteiligte Stoffe

Reaktionsschritte

In a manner similar to the method described in Example 50a, 5-chloro-2-fluorobenzaldehyde (1.2 g, 7.6 mmol) (Aldrich) was reacted with 4-[2-(tert-butyl-dimethyl-silanyloxy)-ethoxy]-phenol (2.1 g, 7.8 mmol) prepared in Example 60b and K2CO3 in N,N-dimethylacetamide at 170° C. for 0.5 h to give 5-chloro-2-[4-(2-hydroxy-ethoxy)-phenoxy]-benzaldehyde as a colorless oil (Yield 1.68 g, 75%).

Herkunft & Nachweise