Methyl 6-chloropyridazine-3-carboxylate → 6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxy}-pyridazine-3-carboxylic acid methyl ester

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Methyl 6-chloropyridazine-3-carboxylate	HCID 12379801	—
Edukt	3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenol	HCID 25254146	—
Produkt	6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenoxy}-pyridazine-3-carboxylic acid methyl ester	HCID 59508643	—

Reaktionsschritte

The title compound was prepared in analogy to Example 93, step 7 from 3-chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenol (obtained in Example 93, step 6) by alkylation with methyl-6-chloropyridazine-3-carboxylate [CAS Reg. No. 65202-50-8]. MS (m/e)=482.0 [MH+].

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08138189B2
Quelldatensatz	uspto-grants-2012_03
ORD ID	ord-581ba622f2674a0f989f0595c4fc0895
Quellennotiz	uspto-grants-2012_03