5-Amino-1-cyclohexyl-5-ethylbarbituric acid → N-(1-Cyclohexyl-5-ethyl-hexahydro-2,4,6-trioxo-5-pyrimidinyl)-2,3,4,5-tetrafluorobenzamide
Reaktionsgleichung
C(N1C(=O)C(N[C:12](=[O:23])[C:13]2[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=2[F:22])(C)C(=O)NC1=O)C.[NH2:26][C:27]1([CH2:42][CH3:43])[C:32](=[O:33])[N:31]([CH:34]2[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35]2)[C:30](=[O:40])[NH:29][C:28]1=[O:41]>>[CH:34]1([N:31]2[C:32](=[O:33])[C:27]([NH:26][C:12](=[O:23])[C:13]3[CH:18]=[C:17]([F:19])[C:16]([F:20])=[C:15]([F:21])[C:14]=3[F:22])([CH2:42][CH3:43])[C:28](=[O:41])[NH:29][C:30]2=[O:40])[CH2:39][CH2:38][CH2:37][CH2:36][CH2:35]1Komponenten
3
Versuchsvorschrift
Compound 20i was prepared by the same method described for 20f using 5-amino-1-cyclohexyl-5-ethylbarbituric acid (0.51 g, 2 mmol). The crude 1-cyclohexyl-5-ethyl-5-(tetrafluorobenzamido)barbituric acid (20i) was obtained as yellow crystals and did not require further purification.
Aufarbeitung
- custom