HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2,3,6-Trifluorobenzaldehyde → [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2,3,6-Trifluorobenzaldehyde | HCID 517845 | — |
| Edukt | 5-(Pyridin-3-yl)-1H-pyrrolo[2,3-b]pyridine | HCID 51358551 | — |
| Edukt | 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine | HCID 58086899 | — |
| Produkt | [5-(3-Methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-(2,3,6-trifluoro-phenyl)-methanone | HCID 58086752 | — |
Reaktionsschritte
was prepared using the protocol of Steps 3 and 4 of Scheme 17, substituting propane-2-sulfonic acid (2,4-difluoro-3-formyl-phenyl)-amide with 2,3,6-Trifluoro-benzaldehyde and 5-pyridin-3-yl-1H-pyrrolo[2,3-b]pyridine 89 with 5-(3-methanesulfonyl-phenyl)-1H-pyrrolo[2,3-b]pyridine in Step 3. MS (ESI) [M−H+]−=429.0.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08143271B2 |
| Quelldatensatz | uspto-grants-2012_03 |
| ORD ID | ord-e9f1e377b6f74de8a46373c27c522164 |
| Quellennotiz | uspto-grants-2012_03 |