Thionyl Chloride → HCID 58087452, Verbindung

Reaktionsgleichung

[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11](O)=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3].S(Cl)([Cl:19])=O>>[CH2:1]([S:4]([NH:7][C:8]1[CH:9]=[C:10]([CH:14]=[CH:15][CH:16]=1)[C:11]([Cl:19])=[O:12])(=[O:6])=[O:5])[CH2:2][CH3:3]

Komponenten

Edukt 2

HCID 24386Thionyl Chloride

HCID 162282623-(Propane-1-sulfonamido)benzoic acid

Produkt 1

HCID 58087452HCID 58087452, Verbindung

Versuchsvorschrift

A solution of 3-(propane-1-sulfonylamino)-benzoic acid (76, 1.20 g, 4.93 mmol) in thionyl chloride was heated to reflux for 3.0 hours. Evaporation of the solvent gave compound 77 as white solid that was used for the next step.

Aufarbeitung

temperatureto reflux for 3.0 hours
customEvaporation of the solvent

Quellen und Nachweise

ORD-Eintrag: ord-71a51daeba604277a775a39195617aa3
Quelldatensatz: uspto-grants-2012_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US08143271B2

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