Trifluoroacetic acid → N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

HRID 1099095Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1099095
[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH:5]C(=O)OC(C)(C)C.[C:19]([OH:25])([C:21]([F:24])([F:23])[F:22])=[O:20]>C(Cl)Cl>[F:22][C:21]([F:24])([F:23])[C:19]([OH:25])=[O:20].[CH3:1][N:2]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=1)[CH2:3][CH2:4][NH2:5]

Komponenten

4

Edukt 2

HCID 6422Trifluoroacetic acidHCID 59216311Tert-butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate

Produkt 1

HCID 66813129N-methyl-N-pyridin-2-ylethane-1,2-diamine trifluoroacetate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6344DichloromethaneLösungsmittel

Versuchsvorschrift

tert-Butyl 2-[methyl(pyridin-2-yl)amino]ethylcarbamate was stirred with DCM (0.5 ml) and TFA (0.5 ml) for 30 min. The volatiles were removed under reduced pressure to yield the product.

Aufarbeitung

  1. customThe volatiles were removed under reduced pressure
  2. customto yield the product

Quellen und Nachweise

ORD-Eintrag
ord-52de3c6fcd584812be89fb6f1cf1a148
Quelldatensatz
uspto-grants-2012_03
Patentnummer
US08143251B2

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