HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Succinic anhydride → (R/S)-1-(1-adamantyl)methyl-2-(2-carboxyethyl)carbonyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Succinic anhydride | HCID 7922 | — |
| Edukt | (R/S)-1-(1-adamantyl)methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole | HCID 53933490 | — |
| Lösungsmittel | 1,4-Dioxane | HCID 31275 | — |
| Produkt | (R/S)-1-(1-adamantyl)methyl-2-(2-carboxyethyl)carbonyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole | HCID 53950661 | — |
Reaktionsschritte
A mixture of (R/S)-1-(1-adamantyl)methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole (640 mg, 2.0 mmol) and succinic anhydride (250 mg, 2.5 mmol) was stirred in dioxan (5 ml) at room temperature for 17 hours. The white precipiate which had formed was isolated by filtration, washed with dioxan and dried. (640 mg, 76%).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06057311 |
| Quelldatensatz | uspto-grants-2000_05 |
| ORD ID | ord-0532127899f14e8aba970fd530a877ab |
| Quellennotiz | uspto-grants-2000_05 |