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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1106933Erstellt: 24. Oktober 2026

Succinic anhydride → (R/S)-1-(1-adamantyl)methyl-2-(2-carboxyethyl)carbonyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole

https://huagongshe.com/de/reaction/1106933

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktSuccinic anhydrideHCID 7922—
Edukt(R/S)-1-(1-adamantyl)methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoleHCID 53933490—
Lösungsmittel1,4-DioxaneHCID 31275—
Produkt(R/S)-1-(1-adamantyl)methyl-2-(2-carboxyethyl)carbonyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indoleHCID 53950661—

Reaktionsschritte

A mixture of (R/S)-1-(1-adamantyl)methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole (640 mg, 2.0 mmol) and succinic anhydride (250 mg, 2.5 mmol) was stirred in dioxan (5 ml) at room temperature for 17 hours. The white precipiate which had formed was isolated by filtration, washed with dioxan and dried. (640 mg, 76%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06057311
Quelldatensatzuspto-grants-2000_05
ORD IDord-0532127899f14e8aba970fd530a877ab
Quellennotizuspto-grants-2000_05