Methyl Palmitate → HCID 15405886, Verbindung

HRID 1107606

Reaktionsgleichung

Reaktionsgleichung von HRID 1107606
[C:1]([O:18]C)(=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16].[OH:20][CH2:21][CH2:22][O:23][CH2:24][CH2:25][NH:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].C(=O)([O-])[O-].[Na+].[Na+]>C(Cl)(Cl)Cl>[CH2:27]([N:26]([CH2:25][CH2:24][O:23][CH2:22][CH2:21][OH:20])[C:1](=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH3:16])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42]

Komponenten

5

Edukt 3

HCID 8181Methyl PalmitateHCID 10340Sodium CarbonateHCID 9996690N-(2-hydroxyethoxy)ethyl-n-hexadecylamine

Produkt 1

HCID 15405886HCID 15405886, VerbindungAusbeute 82 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6212ChloroformLösungsmittel

Reaktionsbedingungen

Temperatur
120 °C

Versuchsvorschrift

Into a 250 ml-flask equipped with reflux condenser, were introduced 14.3 g of methyl palmitate and 16.5 g of N-(2-hydroxyethoxy)ethyl-n-hexadecyl amine prepared in Example 1, and thereto was added 2.6 g of sodium carbonate. Then, the mixture was stirred violently for 3 hours at 120° C. After the termination of the reaction, the mixture was cooled to a room temperature and 100 ml of chloroform was added thereto to be dissolved. The precipitates were removed and the solvent was evaporated off under reduced pressure. The produced solid was recrystallized from hexane to give 23.2 g of the title compound(Yield: 82%) as white powder, which was identified by IR and NMR. The results are shown in Table 1.

Aufarbeitung

  1. customInto a 250 ml-flask equipped
  2. temperaturewith reflux condenser
  3. customAfter the termination of the reaction
  4. temperaturethe mixture was cooled to a room temperature
  5. dissolutionto be dissolved
  6. customThe precipitates were removed
  7. customthe solvent was evaporated off under reduced pressure
  8. customThe produced solid was recrystallized from hexane

Quellen und Nachweise

ORD-Eintrag
ord-6c9600fb39bd4a628153c4c9393e2866
Quelldatensatz
uspto-grants-2000_05
Patentnummer
US06060612

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