Zurück
HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1109276Erstellt: 26. Oktober 2026

Formaldehyde → Dimethyl alpha-hydroxymethyl-alpha-fluoromalonate

https://huagongshe.com/reaction/1109276

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktFormaldehydeHCID 712—
EduktDimethyl fluoromalonateHCID 2737111—
ProduktDimethyl alpha-hydroxymethyl-alpha-fluoromalonateHCID 10910147—

Reaktionsschritte

The process according to the invention for preparing an α-fluoroacrylic acid ester is carried out in three stages. First dimethyl α-fluoromalonate is reacted with formaldehyde to give dimethyl a-hydroxymethyl-α-fluoromalonate, which is then hydrolyzed and the hydrolysis product is dicarboxylated and dehydrated, and finally the resulting α-fluoroacrylic acid is esterified with an alcohol of the formula (3).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05319131
Quelldatensatzuspto-grants-1994_06
ORD IDord-fca26e6d78084861ac2ddc1bf309c09d
Quellennotizuspto-grants-1994_06