HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Benzyl Alcohol → 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzyl alcohol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Benzyl Alcohol | HCID 244 | — |
| Edukt | Acetic Anhydride | HCID 7918 | — |
| Edukt | Isophthalaldehyde | HCID 34777 | — |
| Edukt | 5-Fluoro-2-methylbenzothiazole | HCID 597437 | — |
| Edukt | Sodium borohydride | HCID 4311764 | — |
| Edukt | 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzaldehyde | HCID 86747932 | — |
| Katalysator | Zincchloride | HCID 3007855 | — |
| Lösungsmittel | O-Xylene | HCID 7237 | — |
| Produkt | 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzyl alcohol | HCID 67828433 | — |
Reaktionsschritte
An alternate procedure for preparing this benzyl alcohol comprises condensing isophthalaldehyde with 2-methyl-5-fluorobenzothiazole in the presence of acetic anhydride and zinc chloride in hot xylene followed by the reduction of the 3-(5-fluorobenzothiazol-2-yl-trans-ethenyl)benzaldehyde product with sodium borohydride to provide the appropriate benzyl alcohol.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05322847 |
| Quelldatensatz | uspto-grants-1994_06 |
| ORD ID | ord-bebd70f669a54af8be82f17d90119462 |
| Quellennotiz | uspto-grants-1994_06 |