HCID 13785667, Verbindung → 5-Amino-4-chloro-o-cresol hydrochloride

HRID 1110646Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1110646
[Cl:1][C:2]1[C:7]([N+:8]([O-])=O)=[CH:6][C:5]([OH:11])=[C:4]([CH3:12])[CH:3]=1.[H][H]>C(O)C.[Ni]>[ClH:1].[CH3:12][C:4]1[CH:3]=[C:2]([Cl:1])[C:7]([NH2:8])=[CH:6][C:5]=1[OH:11]

Komponenten

5

Edukt 2

HCID 13785667HCID 13785667, VerbindungHCID 178418361HCID 178418361, Verbindung

Produkt 1

HCID 221538465-Amino-4-chloro-o-cresol hydrochloride

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 935NickelKatalysatorHCID 702EthanolLösungsmittel

Versuchsvorschrift

5 g of 4-chloro-2-methyl-5-nitrophenol were dissolved in 200 ml of ethanol and, after addition of 0.5 g of Raney nickel, the resulting solution was catalytically hydrogenated. When the uptake of hydrogen stopped, the catalyst was separated off by filtration and the filtrate acidified with dilute hydrochloric acid. Concentration to dryness produced light beige crystals melting at 198° C. (with decomposition).

Aufarbeitung

  1. customthe catalyst was separated off by filtration
  2. concentrationConcentration to dryness

Quellen und Nachweise

ORD-Eintrag
ord-aa05f674da744910ab5daf8dcd0502e0
Quelldatensatz
uspto-grants-1990_12
Patentnummer
US04976742

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