Diethylamine → N,N-Diethyl-3-nitrobenzenesulfonamide

HRID 1110672Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1110672
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].[N+:6]([C:9]1[CH:10]=[C:11]([S:15](Cl)(=[O:17])=[O:16])[CH:12]=[CH:13][CH:14]=1)([O-:8])=[O:7]>N1C=CC=CC=1.C(Cl)Cl>[CH2:1]([N:3]([CH2:4][CH3:5])[S:15]([C:11]1[CH:12]=[CH:13][CH:14]=[C:9]([N+:6]([O-:8])=[O:7])[CH:10]=1)(=[O:16])=[O:17])[CH3:2]

Komponenten

5

Edukt 2

HCID 8021DiethylamineHCID 84763-Nitrobenzenesulfonyl chloride

Produkt 1

HCID 232031N,N-Diethyl-3-nitrobenzenesulfonamideAusbeute 51,2 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 1049PyridineLösungsmittel2×HCID 6344DichloromethaneLösungsmittel

Reaktionsbedingungen

Temperatur
50 °C

Versuchsvorschrift

Diethylamine (2.4 g) was dissolved in pyridine (15 ml) and 3-nitrobenzenesulfonyl chloride (6.7 g) was added, followed by stirring at 50° C. for 2 hours. The residue obtained by an evaporation of pyridine under a reduced pressure was dissolved in methylene chloride (150 ml), washed with water, 1N hydrochloric acid, water, and saturated aqueous sodium chloride, and dried over anhydrous sodium sulfate. Evaporation of the solvent under a reduced pressure gave N,N-diethyl-3-(nitro)benzenesulfonamide (4.0 g).

Aufarbeitung

  1. washwashed with water, 1N hydrochloric acid, water, and saturated aqueous sodium chloride
  2. dry with materialdried over anhydrous sodium sulfate
  3. customEvaporation of the solvent under a reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-aa3aa13b3bb74602b666f316a8a8d088
Quelldatensatz
uspto-grants-1990_12
Patentnummer
US04976773

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