Ethyl cyanoformate → Pirolate

HRID 1112241

Reaktionsgleichung

Reaktionsgleichung von HRID 1112241
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]([NH2:15])[C:7]([C:16]([NH2:18])=[O:17])=[CH:6]2.[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])#N>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1[O:13][CH3:14])[N:9]=[C:8]1[N:15]=[C:19]([C:21]([O:23][CH2:24][CH3:25])=[O:22])[NH:18][C:16](=[O:17])[C:7]1=[CH:6]2

Komponenten

4

Edukt 2

HCID 69336Ethyl cyanoformateHCID 7815842-Amino-6,7-dimethoxyquinoline-3-carboxamide

Produkt 1

HCID 135445830Pirolate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

Still further, a mixture of 6,7-dimethoxy-2-aminoquinoline-3-carboxamide (0.5 g., 2 millimoles), ethyl cyanoformate (0.43 g., 44 millimiles) and benzene (30 ml.) is refluxed for three days. The mixture is then cooled, filtered and the solid extracted with chloroform. Concentration of the chloroform extract affords the product which is recrystallized from chloroform.

Aufarbeitung

  1. temperatureis refluxed for three days
  2. temperatureThe mixture is then cooled
  3. filtrationfiltered
  4. extractionthe solid extracted with chloroform
  5. extractionConcentration of the chloroform extract
  6. customaffords the product which
  7. customis recrystallized from chloroform

Quellen und Nachweise

ORD-Eintrag
ord-dd5e7d5fefa5458a8f5c20ee8a84d550
Quelldatensatz
uspto-grants-1978_10
Patentnummer
US04120962

Verknüpfte Notizen

Wird geladen…