HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
UP 614-04 → 2-(1-Phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine maleate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | UP 614-04 | HCID 134375 | — |
| Edukt | Maleic Acid | HCID 444266 | — |
| Edukt | 4-Benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine | HCID 70601820 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 2-(1-Phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine maleate | HCID 86736083 | — |
Reaktionsschritte
18 g of 4-benzyl-2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine are treated as in part (a) of Example 2. After evaporation of the solvent under reduced pressure, 15 g of an oily product are obtained and are dissolved in hot isopropyl alcohol. A hot solution of maleic acid in isopropanol is added. The salt precipitates slowly. 16.5 g of 2-(1-phenyl-2,3-dihydro-benzimidazol-2-on-3-yl-methyl)-morpholine maleate are obtained, m.p. 200° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04122175 |
| Quelldatensatz | uspto-grants-1978_10 |
| ORD ID | ord-b61abd2ebdfc47f9a5d53aede29d595e |
| Quellennotiz | uspto-grants-1978_10 |