Benzyltriphenylphosphonium bromide → 6-Methoxy-2-[2-phenylethenyl]-1H-indole
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([CH:7]=[C:8]([CH:12]=O)[NH:9]2)=[CH:5][CH:4]=1.[Br-].[CH2:15]([P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:1][O:2][C:3]1[CH:11]=[C:10]2[C:6]([CH:7]=[C:8]([CH:12]=[CH:15][C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[NH:9]2)=[CH:5][CH:4]=1Komponenten
3
Versuchsvorschrift
Reaction of 6-methoxyindole-2-carboxaldehyde (145) with benzyltriphenylphosphonium bromide using the procedure described in example 37 gave (146) (94%) as a white solid (mixture of E/Z isomers) which was used without further purification.
Quellen und Nachweise
- ORD-Eintrag
- ord-44e17ed999e24f12a40be8ec409048b0
- Quelldatensatz
- uspto-grants-2006_08