Triethylamine → 2-Isopropoxy-[N-methyl-N-(4-tert-butylphenylthiosulfenyl)carbamoyloxy]benzene

HRID 1112408Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1112408
[CH:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[OH:11])([CH3:3])[CH3:2].[CH3:12][N:13]([S:17][S:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]([CH3:28])([CH3:27])[CH3:26])=[CH:21][CH:20]=1)[C:14](F)=[O:15].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH:1]([O:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[O:11][C:14](=[O:15])[N:13]([CH3:12])[S:17][S:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]([CH3:26])([CH3:28])[CH3:27])=[CH:21][CH:20]=1)([CH3:3])[CH3:2]

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 209492-IsopropoxyphenolHCID 23333006N-Methyl-N(4-t-Butylphenylthiosulfenyl) Carbamoyl Fluoride

Produkt 1

HCID 227640382-Isopropoxy-[N-methyl-N-(4-tert-butylphenylthiosulfenyl)carbamoyloxy]benzeneAusbeute 23,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

To a solution of 4.0 g (0.026 m) of 2-isopropoxyphenol and 7.11 g (0.026 m) of N-methyl-N-(p-tert-butylphenylthiosulfenyl)carbamoyl fluoride in 75 ml of toluene was added 2.63 g (0.026 m) of triethylamine. After stirring for 48 hours the reaction mixture was washed with water and dried over anhydrous MgSO4. The product was purified by dry column chromatography to give 2.5g of a white solid. m.p. 84°-85° C.

Aufarbeitung

  1. washwas washed with water
  2. dry with materialdried over anhydrous MgSO4
  3. customThe product was purified
  4. customby dry column chromatography

Quellen und Nachweise

ORD-Eintrag
ord-645733e2950348eb998225ba5213f8e8
Quelldatensatz
uspto-grants-1978_10
Patentnummer
US04122204

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