2-Pentanamine → N-(1-methylbutyl)-4-(methylsulfonyl)-2,6-dinitro-m-toluidine

HRID 1112567Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1112567
Cl[C:2]1[C:3]([N+:16]([O-:18])=[O:17])=[C:4]([CH3:15])[C:5]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:6][C:7]=1[N+:8]([O-:10])=[O:9].[NH2:19][CH:20]([CH2:22][CH2:23][CH3:24])[CH3:21]>C1C=CC=CC=1>[CH3:21][CH:20]([NH:19][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][C:5]([S:11]([CH3:14])(=[O:13])=[O:12])=[C:4]([CH3:15])[C:3]=1[N+:16]([O-:18])=[O:17])[CH2:22][CH2:23][CH3:24]

Komponenten

4

Edukt 2

HCID 122462-PentanamineHCID 233359733-Chloro-6-(methylsulfonyl)-2,4-dinitrotoluene

Produkt 1

HCID 23335968N-(1-methylbutyl)-4-(methylsulfonyl)-2,6-dinitro-m-toluidine

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 241BenzeneLösungsmittel

Versuchsvorschrift

A mixture of 3-chloro-6-(methylsulfonyl)-2,4-dinitrotoluene (10.0 g., 0.034 mole) and 2-aminopentane (6.1 g. 0.07 mole) is refluxed in benzene (75 ml.) for 4 hours. After standing overnight, the mixture is successively washed with dilute hydrochloric acid, water, a 5% aqueous potassium carbonate solution and finally water. The mixture is then dried over magnesium sulfate. Removal of the magnesium sulfate and solvent leaves the desired product as a yellow oil which readily crystallized on cooling. The crude product is recrystallized from ethanol to give 9.5 grams with m.p. 85°-88° C.

Aufarbeitung

  1. washthe mixture is successively washed with dilute hydrochloric acid, water
  2. dry with materialThe mixture is then dried over magnesium sulfate
  3. customRemoval of the magnesium sulfate and solvent

Quellen und Nachweise

ORD-Eintrag
ord-3a363d62cbe544d189218a9cc54c6667
Quelldatensatz
uspto-grants-1978_10
Patentnummer
US04123250

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