Dichloromethane → 5-{3-[4-Difluoromethyl-6-(6-trifluoromethyl-pyridin-3-yl)-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

Reaktionsgleichung

[C:1]([CH3:2])([CH3:3])([CH3:4])[NH:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:20]3[n:21][c:22](-[c:29]4[cH:30][n:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:23][c:24]([CH:26]([F:27])[F:28])[n:25]3)[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1.[Cl:46][CH2:47][Cl:48].[F:39][C:40]([F:41])([F:42])[C:43]([OH:44])=[O:45]>>[NH2:5][S:6](=[O:7])(=[O:8])[c:9]1[s:10][c:11](-[c:14]2[cH:15][c:16](-[c:20]3[n:21][c:22](-[c:29]4[cH:30][n:31][c:32]([C:35]([F:36])([F:37])[F:38])[cH:33][cH:34]4)[cH:23][c:24]([CH:26]([F:27])[F:28])[n:25]3)[cH:17][cH:18][cH:19]2)[cH:12][cH:13]1