Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|
| Edukt | Water | HCID 962 | — |
| Edukt | Dimethylformamide | HCID 6228 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | Benzo(b)thiophen-4-ol | HCID 19217 | — |
| Edukt | Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1) | HCID 77210 | — |
| Produkt | 2-[(1-Benzothien-4-yloxy)ethyl]morpholine | HCID 86760223 | — |
Reaktionsschritte
4-(2-Chloroethyl)morpholine hydrochloride (0.74 g), 1-benzothiophene-4-ol (0.5 g) and potassium carbonate (1.1 g) in dimethylformamide (15 ml) were heated and stirred at 80° C. for 6 h. After cooling, the mixture was poured into water and extracted twice with ethyl acetate. The combined solvent phase was washed twice with brine, dried (magnesium sulphate) and evaporated to give the product (0.7 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patentnummer | US07098240B2 |
|---|
| Quelldatensatz | uspto-grants-2006_08 |
|---|
| ORD ID | ord-2afdbf5b452c4473aa1f7b3a5c5a3a04 |
|---|
| Quellennotiz | uspto-grants-2006_08 |
|---|
