Hydrazine → HCID 20435928, Verbindung

HRID 1154032Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1154032
[CH3:1][C:2]([CH2:13][CH2:14][O:15][CH:16]1[CH2:21][CH2:20][CH2:19][CH2:18][O:17]1)([C:8](OCC)=[O:9])[C:3](OCC)=[O:4].[NH2:22][NH2:23]>>[CH3:1][C:2]1([CH2:13][CH2:14][O:15][CH:16]2[CH2:21][CH2:20][CH2:19][CH2:18][O:17]2)[C:8](=[O:9])[NH:23][NH:22][C:3]1=[O:4]

Komponenten

3

Edukt 2

HCID 9321HydrazineHCID 20435998HCID 20435998, Verbindung

Produkt 1

HCID 20435928HCID 20435928, VerbindungAusbeute 62 %

Versuchsvorschrift

A mixture of 120.8 g (0.4 mol) of diethyl 2-methyl-2-[2-(tetrahydro-2-pyranyloxy)ethyl]-propane-1,3-dioate and 150 ml of anhydrous hydrazine was heated under reflux for 64 hours. The excess hydrazine was removed by distillation and the residue was recrystallized from methanol to give 60.28 g (62%) of 4-methyl-4-[2-(tetrahydro-2-pyranyloxy)-ethyl]-pyrazolidine-3,5-dione having a melting point of 179°-180° C.

Aufarbeitung

  1. temperaturewas heated
  2. temperatureunder reflux for 64 hours
  3. customThe excess hydrazine was removed by distillation
  4. customthe residue was recrystallized from methanol

Quellen und Nachweise

ORD-Eintrag
ord-6d1dba4ee100425ba9a53fd1dda0cf95
Quelldatensatz
uspto-grants-1984_12
Patentnummer
US04487929

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