1-(2,6-Dichlorophenyl)3-(t-butylcarbamyl)thiourea → 1-(2,6-Dichlorophenyl)-3-carbamylthiourea
Reaktionsgleichung
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH:14]C(C)(C)C)=[S:11]>Cl>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:19])[NH2:14])=[S:11]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
A mixture of 32 g (0.1 mole) of 1-(2,6-dichlorophenyl)-3-(t-butylcarbamyl)thiourea and 200 ml of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, filtered and washed with 10 ml of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanol-ether to obtain 1-(2,6-dichlorophenyl)-3-carbamylthiourea.
Aufarbeitung
- temperatureis refluxed for 1/2 hour
- temperatureThe reaction mixture is cooled
- filtrationfiltered
- washwashed with 10 ml of 1:1 HCl/H2O
- customdried
- customThe product is then recrystallized from ethanol-ether
Quellen und Nachweise
- ORD-Eintrag
- ord-dab20c9387d340cda0ec8a4bcbed35b3
- Quelldatensatz
- uspto-grants-1984_12
- Patentnummer
- US04488993
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